Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.600 None 0.867 3 0 1993 2019
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
sirtuin 1 0.378 0.885 8.7E-02
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.220 None 1.000 2 0 2008 2019
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3
forkhead box O3 0.431 0.808 0.99
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.220 None 1.000 1 0 2008 2019
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
angiotensin I converting enzyme 2 0.477 0.769 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.280 None 1.000 1 0 2006 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.210 None 1.000 1 0 2008 2019
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
NADPH oxidase 4 0.471 0.885 5.8E-20
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.210 None 1.000 1 0 2013 2019
Entrez Id: 4879
Gene Symbol: NPPB
NPPB
natriuretic peptide B 0.513 0.808 9.9E-06
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.250 None 1.000 2 0 2006 2018
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.600 None 0.941 1 0 1993 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.520 None 1.000 1 0 2004 2018
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.240 None 0.800 1 0 2009 2018
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.359 0.962 1.6E-10
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.210 None 1.000 1 0 2009 2018
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
nitric oxide synthase 3 0.378 0.885 6.7E-07
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.270 None 1.000 1 0 1997 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.210 None 1.000 1 0 2013 2017
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
endothelin 1 0.380 0.846 0.46
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.550 None 1.000 2 0 1997 2016
Entrez Id: 4625
Gene Symbol: MYH7
MYH7
myosin heavy chain 7 0.516 0.692 4.2E-16
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.330 None 1.000 1 0 1987 2016
Entrez Id: 522
Gene Symbol: ATP5PF
ATP5PF
ATP synthase peripheral stalk subunit F6 0.716 0.538 6.1E-03
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2015 2015
Entrez Id: 513
Gene Symbol: ATP5F1D
ATP5F1D
ATP synthase F1 subunit delta 0.674 0.500 7.4E-02
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2015 2015
Entrez Id: 156
Gene Symbol: GRK2
GRK2
G protein-coupled receptor kinase 2 0.532 0.654 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.220 None 1.000 1 0 1999 2015
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
natriuretic peptide A 0.505 0.769 5.5E-04
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.560 None 1.000 2 0 1997 2014
Entrez Id: 4691
Gene Symbol: NCL
NCL
nucleolin 0.509 0.808 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2014 2014
Entrez Id: 4881
Gene Symbol: NPR1
NPR1
natriuretic peptide receptor 1 0.608 0.654 2.9E-04
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.210 None 1.000 1 0 2006 2014
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1
polybromo 1 0.566 0.615 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
ADAM metallopeptidase domain 17 0.453 0.808 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 6597
Gene Symbol: SMARCA4
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.450 0.885 1.00
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2013 2013
Entrez Id: 6604
Gene Symbol: SMARCD3
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 0.821 0.269 0.40
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
disease 0.200 None 1.000 1 0 2013 2013